01ai2019–2026
London legal tech fine-tuned Anthropic's Claude for contracts, raised ~$64M, then a failed 2025 raise split it: Scissero took services, Microsoft took the team.
Read the case ↗02bio2025–2026
Three founders turned Orthrus — a 10M-parameter RNA model that outperforms 40B-parameter Evo2 on mRNA benchmarks — into a YC-backed RNA therapeutics toolkit.
Read the case ↗03climate2021–2025
Group14's SCC55 silicon anode began shipping from its Sangju factory in September 2024; $463M Series D in 2025 pushed total equity past $1B.
Read the case ↗04commerce2012–2026
Rocket Internet's 2012 bet on an 'Amazon of Africa' reached a $1B valuation and NYSE IPO, crashed 90%, and now targets 2027 profit.
Read the case ↗05consumer2011–2025
CaaStle raised $530M+ to sell fashion rental-as-a-service, then filed Chapter 7 in June 2025 after its founder admitted a $300M fraud.
Read the case ↗06education2024–2026
Unacademy's AI-native language app went global with 10M learners in 150 countries; became top-3 downloaded language app worldwide.
Read the case ↗07fintech2015–2026
Berlin insurtech raises $1B+ and peaks at $4.5B, then a 2024 cash crunch forces exits, a new CEO and a €151M rescue.
Read the case ↗08frontier2018–2026
Archer Aviation built the Midnight eVTOL on United's $1B order, betting FAA's 2024 powered-lift rule opens air taxis; first to clear certification Phase 3.
Read the case ↗09hardware2016–2026
Seattle's Picnic bet stadiums and chains would lease robotic pizza assemblers; after $53M and a Domino's pilot it never profited, then liquidated in May 2026.
Read the case ↗10health2024–2026
YC W25 startup automates referral intake for specialist clinics — parsing faxes, verifying insurance and scheduling so patients stop falling through the cracks.
Read the case ↗11logistics2017–2026
Two Ford engineers pivoted from hybrid bikes to fleet software, digitized Indonesia's trucking fleets, and hit EBITDA-positive ground before a $9M Series B.
Read the case ↗12tools2026
Duc-Tam Nguyen's Go CLI renders pages in headless Chrome, strips all JavaScript, then packs the site as a ZIM file or single binary; Show HN: 712 points.
Read the case ↗13ai2019–2026
Tsinghua spinout Zhipu (Z.ai) bet original GLM architecture, open weights and phone-controlling agents could make China's OpenAI; HK IPO Jan 2026, stock up 13x.
Read the case ↗14bio2007–2026
Keio-spun Spiber raised $640M+ to ferment spider-silk-style fibers, sold a North Face Moon Parka, then defaulted on ¥35B and entered special liquidation.
Read the case ↗15climate2019–2026
Watershed bet EU CSRD and California's SB 253 would make carbon reporting audit-grade compliance; it became climate software's most valuable company at $1.8B.
Read the case ↗16commerce2025–2026
Swiggy's budget counter to Rapido: toing — meals under ₹250 with no packaging fees — passed 1M downloads and hit #25 on India's iPhone charts.
Read the case ↗17consumer2025–2026
Three part-time devs spent ¥1,500 betting solo dwellers would pay for a blunt safety check-in app; it went viral in Jan 2026, then forced a rename.
Read the case ↗18education2021–2026
Two immigrant founders grew BoldVoice from Reddit accent communities to $10M ARR, 5M+ downloads and a Matrix-led $21M Series A.
Read the case ↗19fintech2019–2025
Nigeria's open-banking pioneer wound down in May 2025 after six years, refunding investors and sending its co-founder to UK startup Kernel
Read the case ↗20frontier2021–2026
Founded 2021, raised ¥15.27B in 2025, valuation ¥60B, E2E route unproven.
Read the case ↗